Multifocal Medulloblastoma in an Adult Patient: Description of a Rare Presentation and Review of the Literature

Figure 3

Immunohistochemical panels of the two excised lesions. (a, b) Tumors are strongly positive for synaptofisin (original magnification x4 (a), x10 (b)). (c, d) Beta-catenin has a cytoplasmic distribution (original magnification x10). (e, f) YAP1 is diffusely positive (original magnification x10). (g, h) GAB1 is positive and diffuse in the right cerebellar lesion and predominantly internodular in the left lesion (original magnification x10). (i, j) Tumor cells maintain the expression of INI-1 (original magnification x10). (k, l) Tumor cells maintain the expression of BRG1 (original magnification x10).

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