Metaplastic Carcinoma of the Breast with Squamous Differentiation: A Case Report from the University Teaching Hospital of Kigali (CHUK), Rwanda

Figure 1

Photomicrographs of a breast metaplastic carcinoma. (a) Low magnification showing a solid trabecular tumor exhibiting keratin pearls and infiltrating the desmoplastic stroma (H&E, x40). (b) High magnification shows nests of cohesive, large polygonal cells with eosinophilic cytoplasm, and large nuclei with prominent nucleoli; necrosis and cavitation are seen on the right lower field (H&E, x200). (c) The tumor is negative for ER (immunoperoxidase, x200). (d) The tumor is negative for HER2/neu (immunoperoxidase, x200).

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