Focal Segmental Glomerulosclerosis Preceding Type 2 Papillary Renal Cell Carcinoma

Figure 4

FSGS: (a) renal cortex with glomerulosclerosis and focal interstitial fibrosis, H&E stain (100x magnification). (b) Global glomerulosclerosis, PAS stain (200x magnification). Normal glomeruli, by definition, must coexist with the pathological process for the diagnosis of FSGS, PAS stain (c) and silver stain (d) (200x magnification). Electron microscopy: (e) foot process effacement, epithelial cell detachment from glomerular basement membrane, and capillary wrinkling (15,000x magnification). (f) Retraction of tufts and wrinkling of capillary walls (12,000x magnification).

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