Case Report
Plasmablastic Lymphoma Associated with Adjacent Mature Plasma Cell Population Exhibiting Opposite Light Chain Restriction
Table 2
Summary of cases published in the literature to date of plasmacytomas progressing to PBL.
| Case | Age/sex | HIV/posttransplant | Location | Ki-67 | c-MYC IHC | FISH (MYC) | Monoclonal IGHV | Bone marrow | Treatment | Survival |
| 1 (Saito et al.) | 34/M | (-/-) | Ileocecal with lymph node involvement | 80-90% | Unknown | Unknown | Unknown | Negative | R-CHOP | 7.5 years, still alive | 2 (Ambrosio et al.) | 74/M | Unknown | Maxillary sinus | 95% | Positive | Negative | Positive | Negative | Complex (primarily CyBorD) | Disease free 11 months | 3 (Qing et al.) | 69/M | (-/-) | Generalized lymphadenopathy | 95% | Unknown | Unknown | Unknown | Negative | CHOP | Alive; unclear on time frame | 4 Current case | 78/F | (-/-) | Maxillary sinus | 95% | Positive | MYC amplification | Inconclusive | Mature appearing kappa restricted plasma cell population, no evidence of PBL | R-CHOP | Disease-free after 6 months |
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