Case Report

Plasmablastic Lymphoma Associated with Adjacent Mature Plasma Cell Population Exhibiting Opposite Light Chain Restriction

Table 2

Summary of cases published in the literature to date of plasmacytomas progressing to PBL.

CaseAge/sexHIV/posttransplantLocationKi-67c-MYC IHCFISH (MYC)Monoclonal IGHVBone marrowTreatmentSurvival

1 (Saito et al.)34/M(-/-)Ileocecal with lymph node involvement80-90%UnknownUnknownUnknownNegativeR-CHOP7.5 years, still alive
2 (Ambrosio et al.)74/MUnknownMaxillary sinus95%PositiveNegativePositiveNegativeComplex (primarily CyBorD)Disease free 11 months
3 (Qing et al.)69/M(-/-)Generalized lymphadenopathy95%UnknownUnknownUnknownNegativeCHOPAlive; unclear on time frame
4 Current case78/F(-/-)Maxillary sinus95%PositiveMYC amplificationInconclusiveMature appearing kappa restricted plasma cell population, no evidence of PBLR-CHOPDisease-free after 6 months