| | Author | # case | Gender, age, risk factors | Tumor size (mm) | Extrathyroid extension at diagnosis | LN metastasis at diagnosis | Distant metastasis at diagnosis | Neoadjuvant therapy | Surgery | Adjuvant therapy | Follow-up status |
| | Eusebi et al. [13] | #4 | F, 61 y/o | 40 | N/A | N/A | N/A | None | Lobectomy | None | 24 months | | Lamovec et al. [19] | #1 | F, 64 y/o, goiter | 40 | No | No | No | No | L’t total and R’t subtotal lobectomy | R/T | 36 months | | Maiorana et al. [11] | #1 | F, 84 y/o, goiter | 30 | No | N/A | No | None | TT | None | 66 months | | #3 | F, 69 y/o, goiter | 50 | No | N/A | No | None | TT | None | 32 months | | #4 | F, 60 y/o, goiter | 3 masses; up to 25 | No | N/A | No | None | TT | None | 27 months | | Ryska et al. [3] | #3 | F, 60 y/o | 70 | N/A | No | N/A | N/A | N/A | N/A | 21 months | | Innaro et al. [28] | | F, 49 y/o, goiter | 75 | No | Yes | No | None | TT+neck LND | C/T | 22 months totally (postoperative residual lymphadenopathy S/P adjuvant C/T; then NED for 16 months) | | Altinay et al. [32] | | F, 62 y/o, goiter | 30 | No | N/A | N/A | None | TT | None | 15 months | | Couto et al. [33] | | F, 61 y/o | 35 | No | N/A | N/A | None | TT | R/T | 72 months totally (2 months after surgery, locally recurred, S/P tumor excision+R/T, then NED for 48 months) | | Yoon Moon et al. [5] | | F, 48 y/o | N/A | Yes | N/A | N/A | None | TT+partial resection of the trachea | R/T | 24 months | | Collini et al. [4] | #3 | M, 56 y/o | 50 | Yes | No | No | None | TT | C/T and R/T | 82 months | | #4 | F, 63 y/o | 130 | Yes | No | No | C/T | TT | C/T | 70 months | | #5 | M, 53 y/o | 50 | Yes | No | No | None | TT | C/T | 59 months totally (8 months after surgery, locally recurred, S/P C/T+tumor excision), NED for 51 months, then lost to follow-up | | Marina et al. [6] | | M, 63 y/o, radiation exposure, goiter | 120 | No | No | No | None | TT+neck LND | C/T | 62 months | | Nechifor-Boilă et al. [38] | #1 | F, 74 y/o, goiter | 70 | No | N/A | N/A | None | TT | None | 40 months | | #2 | M, 70 y/o, goiter | 80 | Yes | No | No | None | TT+neck LND | R/T | 73 months |
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