Serum Cytokine Concentrations in a Patient with Rheumatoid Arthritis on Etanercept Therapy Who Subsequently Developed Pneumocystis Pneumonia: A Case Report
Figure 2
Time course of serum cytokines concentrations from baseline to 8 days. (a) TNF-alpha was not detectable in baseline samples. One day after the start of etanercept therapy TNF-alpha was measurable by ELISA. TNF-alpha levels became steady within 2 days of etanercept therapy. TNFR-II concentrations became elevated after the start of etanercept therapy. Within the first week of etanercept therapy, TNFR-II reached levels ranging from 160 ng/mL to 190 ng/mL. (b) Serum IL-6, IL-1 beta, and CRP concentrations were decreased just after the initiation of treatment.
