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Case Reports in Rheumatology
Volume 2011, Article ID 195085, 4 pages
Case Report

Disseminated Tuberculosis Mimicking Ankylosing Spondylitis

1Department of Nuclear Medicine, Hôpital Erasme, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium
2Department of Rheumatology, Hôpital Erasme, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium

Received 7 June 2011; Accepted 6 July 2011

Academic Editors: D. Aeberli, R. Cevik, and F. Maillot

Copyright © 2011 Valérie Huyge et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Ankylosing spondylitis is a chronic inflammatory disorder affecting mainly the axial skeleton. Here we report a case of a man with a clinical suspicion of ankylosing spondylitis but with a persistence of increased inflammatory markers. In this case, 18F-FDG-PET/CT revealed multiple hypermetabolic lesions in axial skeleton, lymph nodes, and the lung, suggestive of either disseminated tuberculosis or lymphoma. Histological analysis of the pulmonary lesion revealed mycobacterium tuberculosis. This case highlights, firstly, the importance of excluding other diagnoses in the presence of clinical picture of ankylosing spondylitis and high inflammatory markers and, secondly, the determining role of PET/CT.