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Case Reports in Rheumatology
Volume 2013, Article ID 840984, 4 pages
Case Report

Pachymeningitis in Granulomatosis with Polyangiitis: A Case Report and a Review of the Literature

1Department of Rheumatology, 424 General Military Hospital, 564 03 Thessaloniki, Greece
2Department of Internal Medicine, 424 General Military Hospital, 564 03 Thessaloniki, Greece

Received 26 June 2013; Accepted 17 July 2013

Academic Editors: J. V. Dunne and P. E. Prete

Copyright © 2013 Grigorios T. Sakellariou and Nicoleta Kefala. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Central nervous involvement, mainly with symptoms of cranial neuropathies, occurs in 2–8% of patients with granulomatosis with polyangiitis (GPA). Meningeal involvement, with persistent and severe headache as main manifestation and abnormal thickening and enhancement of the dural mater on postcontrast magnetic resonance imaging, is extremely rare. We present a case of pachymeningitis due to limited GPA, providing simultaneously a literature review.