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Case Reports in Rheumatology
Volume 2014, Article ID 291382, 3 pages
Case Report

Treatment Resistant Severe Digital Ischemia Associated with Antiphospholipid Syndrome in a Male Patient with Systemic Sclerosis

1Department of Rheumatology, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, Turkey
2Department of Internal Medicine, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, Turkey

Received 22 May 2014; Accepted 27 June 2014; Published 8 July 2014

Academic Editor: Tsai-Ching Hsu

Copyright © 2014 Orhan Küçükşahin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We report the case of a male patient with limited cutaneous systemic sclerosis (SSc) that was complicated with severe digital ischemia, resistant to medical treatment. Due to the lack of treatment response, further laboratory and imaging studies were conducted. Findings were compatible with antiphospholipid syndrome and oral warfarin was added to the treatment regimen. After successful anticoagulation no further recurrences of digital ischemia were seen. An underlying etiology in SSc patients with treatment resistant digital ischemic necrosis should be suspected for accompanying antiphospholipid syndrome (APS).