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Case Reports in Rheumatology
Volume 2014 (2014), Article ID 358567, 3 pages
Case Report

Lung Sarcoidosis in Etanercept Treated Rheumatoid Arthritis Patient: A Case Report and Review of the Literature

Mount Sinai School of Medicine, Queens Hospital Center, Jamaica, NY 11432, USA

Received 18 January 2014; Accepted 23 June 2014; Published 3 July 2014

Academic Editor: Suleyman Serdar Koca

Copyright © 2014 Supat Thongpooswan and Adriana Abrudescu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We report a 55-year-old female with seropositive rheumatoid arthritis for 10 years who developed large mediastinal and hilar adenopathy while receiving etanercept therapy. Chest high resolution computed tomography (HRCT) showed mediastinal lymph nodes with size of centimeters. Right paratracheal lymph node biopsy showed nonnecrotizing epithelioid granulomata. All infectious studies of pulmonary lymph node tissues were negative. Etanercept was discontinued. Follow-up HRCT 6 months later showed resolution of mediastinal lymph nodes. This report should increase awareness of pulmonary sarcoidosis development in patient treated with tumor necrosis factor-alpha blocking agent, etanercept.