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Case Reports in Rheumatology
Volume 2015, Article ID 108459, 5 pages
Case Report

Sarcoidosis and Histoplasmosis: Is One a Consequence of the Other? A Case Report and Review of the Literature

1Atlantic University School of Medicine, Gros Islet Highway, Rodney Bay, Saint Lucia
2Phoenix Children’s Hospital, 1919 E. Thomas Road, Phoenix, AZ 85016, USA

Received 17 April 2015; Revised 13 July 2015; Accepted 15 July 2015

Academic Editor: Mario Salazar-Paramo

Copyright © 2015 Anupam Bansal and Rupali Drewek. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Sarcoidosis involves abnormal collections of inflammatory cells (granulomas) which may form as nodules in multiple organs. 90% of affected patients have respiratory tract abnormalities. We present a 61-year-old male with sarcoidosis who was admitted for respiratory distress. Fibrosing mediastinitis was seen in the chest computograph. Management was conservative and included steroids, antibiotics, and oxygen therapy. Sarcoidosis and fibrosing mediastinitis are rare. Fibrosing mediastinitis is more commonly seen with histoplasmosis. We explore the clinical similarities between histoplasmosis and sarcoidosis. We also explore the potential cause and effect relationship and workup for each disease entity.