Cutaneous Ulcers as Initial Presentation of Localized Granulomatosis with Polyangiitis: A Case Report and Review of the Literature

Table 1

Laboratory data.

Investigations	Results
Hb/Hct	10.5/35
WBC	8.5 × 10^9/L
Platelet count	226 × 10^9/L
Blood urea nitrogen	12 mg/dL
Serum creatinine	0.8 mg/dL
Total bilirubin (direct/indirect)	0.7 mg/dL (0.5/0.2)
Alanine aminotransferase	13 U/L
Alkaline phosphatase	107 U/L
Urinalysis	pH: 5.5, no glucose/ketones/casts/protein, WBCs 3-4/high power field
Blood cultures (3 sets)	No growth
Urine culture	No growth
Interferon gamma release assay (IGRA)	Negative
Brucella abortus and melitensis titres	<1 : 80 ×2
Hepatitis B surface antigen (HBsAg)	Negative
Anti-HCV antibody	Negative
Antinuclear antibody	Negative
Anti-dsDNA	Negative
ACCP antibody	Negative
QRA	27.7 (elevated)
c-ANCA	Negative (0.8 U/mL)
p-ANCA	Negative (1.86 U/mL)
Angiotensin converting enzyme	40 U/L (normal <52 U/L)