Case Reports in Rheumatology / 2015 / Article / Tab 1

Case Report

Fatal Cytomegalovirus Disease after Combination Therapy with Corticosteroids and Rituximab for Granulomatosis with Polyangiitis

Table 1

Time course of illness with corresponding PR3 level, treatment regimen, and reactivation of CMV disease.

Day 5Day 10Day 20Day 25Day 30Day 40

PR3 level1351767383310150

CorticosteroidPrednisone
80 mg
Prednisone
80 mg
Prednisone
80 mg
Prednisone
70 mg
Prednisone
70 mg
Prednisone
70 mg

RituximabSecond doseThird doseFourth dose

Symptoms and signs of CMV diseaseHypoxia, feverWorsening pulmonary infiltratesPersistent viremia

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