Case Report

Three Cases of Previous Smokers with Rheumatoid Arthritis Who Did Not Respond to Tumor Necrosis Factor Inhibitors Were Treated Successfully with an Anti-Interleukin-6 Receptor Antibody

Figure 1

Summary of the clinical course of case 1. DAS28-CRP Disease Activity Score assessing 28 joints with C-reactive protein. SASP: salazosulfapyridine, PSL: prednisolone, ETN: etanercept, TCZ: tocilizumab, and MMP-3: matrix metalloproteinase-3. TJ means tender joint counts and SJ means swollen joints counts for the assessment of DAS 28-CRP. The asterisk shows the cessation of smoking. Etanercept was initiated 1.5 years after the cessation of smoking.