Case Report

Chronic and Asymptomatic Diffuse Alveolar Haemorrhage with Microscopic Polyangiitis: A Case Report and Review of the Literature

Table 1

Clinical characteristics of cases of chronically progressive DAH with MPA reported in the literature, including the present case.

Ref. numberAgeGender (M/F)Detected antibodyDuration at the onset of DAHRespiratory symptomsComplicationsinflammatory reaction such as fever, CRP titre

[5]61FAnti-GBM antibody, ANCA2 yearsBreathlessRenal failure, anaemia
(Hb 6.0 g/dL)
N.A.
[6]23FMPO-ANCA4 yearsNoRenal failure, anaemia
(Hb 6.3 g/dL)
no fever, normal CRP titre, 80 mm/h of ESR
[7]11FMPO-ANCA1 yearNoanaemia
(Hb 5.9 g/dL)
no fever
Present case78FMPO-ANCAMore than
3 months
NoRenal failure, anaemia
(Hb 6.9 g/dL)
no fever, normal CRP titre

GBM: glomerular basement, ANCA: anti-neutrophil cytoplasmic antibody, MPO-ANCA: myeloperoxidase anti-neutrophil antibody, Hb: haemoglobin, CRP: C-reactive protein, and ESR: erythrocyte sedimentation rate.