Eltrombopag Improves Refractory Thrombocytopenia in a Patient with Systemic Lupus Erythematosus

Figure 2

Microscopy of a renal biopsy specimen. (a) There are mainly chronic inactive lesions with scarring, though endocapillary glomerulonephritis is partially noted (arrow). Diffuse thickening of glomerular capillaries is seen. (b) Immunofluorescence is weakly positive for granular deposits of IgG, IgM, C3, and C1q along the GBM. Analysis of IgG subclasses revealed deposition of IgG1. (c) Electron microscopy shows subepithelial and intramembranous electron-dense deposits (EDD; small arrow) and electron-lucent deposits (large arrow), along with partial mesangial and subendothelial EDD.

(a)

(b)

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