Cutaneous Polyarteritis Nodosa Presenting Atypically with Severe Pharyngeal Ulceration

Figure 2

(a) H and E stained skin punch biopsy (x20 magnification) showing loss of the epidermis with an inflammatory infiltrate in the dermis composed of neutrophils and histiocytes, the latter coalescing into (b) poorly formed granulomas (x100 magnification). Abundant cytoclastic debris is present. (c) In areas the inflammation appears centred on blood vessels associated with fibrinoid necrosis (x200 magnification). The findings indicate a necrotising vasculitis with granulomatous features.

(a)

(b)

(c)