Case Report

Pancreatic Cancer and Primary Sjögren’s Syndrome: A Case Report

Table 1

Main original studies assessing solid cancer risk in primary SS.

Author, country, yearStudy designNumber of patients with primary SS includedType of malignancy associated

Insler and Shelin; USA; 1987 [17]Case report1Thymoma
Janssens et al.; Belgium; 1987 [11]Case report1Primary SS as paraneoplastic syndrome
Matsumoto et al; Japan; 1996 [16]Case report1Thymoma
Theander et al.; Sweden; 2006 [20]Retrospective cohort507Lymphoproliferative malignancy
Lazarus et al.; England; 2006 [2]Retrospective cohort112Lymphoproliferative and multiple myeloma
Gadalla et al.; USA; 2009 [21]Retrospective case -control196Breast cancer
Zhang et al.; China; 2010 [1]Retrospective cohort1320Lymphoproliferative malignancy, multiple myeloma; thymoma; oral cavity and breast
Bartoloni et al.; Italy; 2012 [10]Case report1Primary SS as paraneoplastic syndrome
Weng et al; Taiwan, 2012 [3]Retrospective cohort7852Thyroid
Boussios et al.; Greece; 2014 [13]Retrospective cohort450Lymphoproliferative malignancy
Lai et al.; Taiwan 2014 [5]Case report1Nasopharyngeal
Yu et al.; Taiwan; 2016 [15]Retrospective cohort11998Nasopharyngeal, thyroid, and lung
Brito Zéron et al.; Spain; 2017 [4]Retrospective cohort1300Oral cavity, thyroid, and stomach
Brom et al.; Argentine; 2019 [14]Retrospective cohort157Oral cavity and breast
Tarhan et al.; Turkey; 2019 [22]Retrospective cohort8Breast
Findakly; USA; 2020 [8]Case report1Gastric adenocarcinoma
Kang et al.; South Korea; 2020 [6]Retrospective cohort6359Oropharynx, thyroid, liver, and lung (more common); pancreatic cancer
Mathews et al.; USA; 2020 [7]Retrospective cohort126Lymphoproliferative malignancy, breast, and thyroid (more common); pancreatic cancer

Out of 84,778 breast cancer patients; out of 128 breast patients.