Case Report
Neuropsychiatric Lupus and Lupus Nephritis Successfully Treated with Combined IVIG and Rituximab: An Alternative to Standard of Care
Table 1
Laboratory data through the course.
| | Variable | On presentation to the OPD | During sepsis | After combined rituximab and IVIG | Reference range |
| | WBC count (103/μl) | 3.84 | 17.53 | 4.90 | 4.5–11 | | Deferential count | | Neutrophils (%) | 51.30 | 91.50 | 46.50 | 35–80 | | Lymphocytes (%) | 42.70 | 5.00 | 39.00 | 24–44 | | Monocytes (%) | 4.20 | 3.20 | 12.90 | 4.7–12.5 | | Eosinophils (%) | 1.80 | 0.10 | 1.40 | 0–4 | | Basophils (%) | 0.00 | 0.20 | 0.20 | 0–1 | | RBC count (106/μl) | 3.28 | 3.67 | 5.73 | 4.3–5.7 | | Hemoglobin (g/dl) | 8.50 | 10.10 | 14.60 | 13.2–17.3 | | Hematocrit (%) | 28.20 | 31.40 | 45.00 | 39–49 | | MCV (fL) | 86.00 | 85.60 | 78.50 | 80–100 | | MCH (pg) | 26.00 | 27.50 | 25.50 | 26–34 | | MCHC (g/dl) | 30.10 | 32.20 | 32.40 | 32–36 | | RDW (%) | 16.30 | 15.60 | 15.20 | 11.6–14.6 | | Platelet count (103/μl) | 351.00 | 261.00 | 241.00 | 150–440 | | C-reactive protein (mg/L) | 5.33 | 232.70 | — | 0–3.0 | | Antinuclear antibodies | 262.20 | — | — | <20 | | Anti-Smith antibody (CU) | >693.50 | — | — | <20 | | Anti-ribonuclear protein (CU) | >643.80 | — | — | <20 | | Anti-SCL-70 (unit) | 35.90 | — | — | <20 | | Anti-dsDNA antibodies (IU/ml) | >666.90 | >666.90 | 55.30 | <27 | | Complement 3 (g/l) | 0.13 | 0.40 | 0.79 | 0.9–1.8 | | Complement 4 (g/l) | 0.01 | 0.06 | 0.16 | 0.1–0.4 | | Creatinine (mg/dl) | 0.76 | 2.27 | 0.83 | 0.67–1.17 | | Creatinine kinase (U/l) | 630.00 | 36.00 | — | 39–308 | | Protein/creatinine ratio (mg/g) | 373.72 | — | 144.02 | <200 | | Albumin/creatinine ration (mg/g) | — | 1560.84 | — | — | | Protein (CSF) (mg/dl) | — | 113.50 | — | 15–45 | | Glucose (CSF) (mg/dl) | — | 45.40 | — | 40–70 | | Total leukocytes (CSF) (/MicroL) | — | 4.00 | — | — |
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