Kikuchi-Fujimoto Disease: A Differential for When It is Not Systemic Lupus Erythematosus
Table 2
Immunological tests.
Item
Reference range
Results
Anti-nuclear antibody (ANA) with HEp-2 substrate Immunofluorescence assay (IFA)
Positive
ANA titer
<1 : 40
1 : 40
1 : 40–1 : 80 weakly positive
> Or = to 1 : 160 result may be clinically significant
ANA pattern
Nuclear, speckled
Anti-jo-1 Ab
<9 IU/mL
<1.0
Centromere B Ab
<9 IU/mL
<1.0
Complement C3
82–185 mg/dL
129
Complement C4
15–53 mg/dL
37
Rheumatoid factor
<14 IU/mL
<14
16
Negative ≤4 IU/mL
Anti-DNA, native double strand IgG ELISA
Indeterminate 4–9 IU/mL
Positive ≥10 IU/mL
Thyroid peroxidase (TPO) Ab
<9 IU/mL
<1
Ribosomal P protein Ab
<1.0 NEG AI
<1.0
Scleroderma (SCL-70)
<1.0 NEG AI
<1.0
Sjögren Ab SSA
<1.0 NEG AI
3.3
Sjogren Ab SSB
<1.0 NEG AI
<1.0
Anti-smith antibody
<1.0 NEG AI
<1.0
Sm/RNP
<1.0 NEG AI
<1.0
Histone Ab
<1.0 NEG AI
<1.0
CRP
<1.0 mg/dL
<0.40
ESR
0–20 mm/HR
16
CCP Ab IgG
0.0 to 5.0 unit: U/mL
<16
Cardiolipin Ab IgG
<20 GPLU/mL
<14
Cardiolipin Ab IgM
<20 MPL U/mL
<12
Cardiolipin Ab IgA
<22 APL U/mL
<11
Lupus anticoagulant
Not detected
Not detected
PTT-LA screen
28.0 to 43.0 secs
<31
dRVVT screen
<42.9 secs
<38
B2 glycoprotein I IgG Ab
<20 G units
<9
B2 glycoprotein I IgA Ab
<20 A units
<9
B2 glycoprotein I IgM Ab
<11 M units
<9
Triiodothyronine
76–181 ng/dL
118
HEp-2: human larynx epithelioma cancer (HEp-2) cell lines. IgG ELISA: immunoglobulin G enzyme-linked immunoassay. Extractable nuclear antigen: run on enzyme-linked immunoassay (ELISA) assay kit.
