Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom Trajectory

Figure 1

Definitions of the four PD subtypes and the depressive symptom trajectory from the perinatal period to 5 years postpartum. (a) According to four measurements of depressive symptoms during the perinatal period, four PD subtypes, pregnancy, early postpartum, late postpartum, and chronic PD, were defined. The “○” symbol represents “depressive,” and the “-” symbol represents “not depressive.” (b) Participants responded to K6 twice during pregnancy, EPDS at 1 month and 6 months postpartum, and K6 annually thereafter. Each line represents PD subtypes and healthy participants. The -axis represents the time of the questionnaire, and the -axis represents the mean questionnaire score in each group.

(a)

(b)