The In Vitro Susceptibility of Biofilm Forming Medical Device Related Pathogens to Conventional Antibiotics

Figure 4

Log₁₀ graph showing biofilm eradication kinetics and Log₁₀ biofilm viable counts (Log₁₀ CFU/peg) of S. aureus (ATCC 29213) (positive control: filled diamonds, full line) over a period of 24 hours of exposure to MBEC value (mg L⁻¹) of active standard antimicrobials (rifampicin 15.63 mg L⁻¹: filled triangle, full line; gentamicin 15.63 mg L⁻¹: cross, dotted line; ciprofloxacin 500 mg L⁻¹: full circle, full line) based on five replicates. Trimethoprim and vancomycin had MBEC values greater than 1000 mg L⁻¹ against S. aureus (ATCC 29213) and therefore were not tested for biofilm eradication kinetics.