Table of Contents
Dataset Papers in Science
Volume 2014, Article ID 376541, 3 pages
Dataset Paper

Comprehensive Analysis of MicroRNA and mRNA Expression in Normal and Tumorous Human Esophageal Squamous Cell Lines Using Microarray Datasets

1Department of Surgery, Nippon Medical School Tama Nagayama Hospital, Tokyo 206-8512, Japan
2Laboratory of Biological Macromolecules, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai 599-8531, Japan
3Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo 113-8602, Japan
4Department of Surgery, Nippon Medical School Chiba Hokusou Hospital, Inzai, Chiba 270-1694, Japan

Received 5 October 2014; Accepted 13 November 2014; Published 15 December 2014

Academic Editor: Qinghua Cui

Copyright © 2014 Ichiro Akagi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Despite the undisputed importance of altered microRNA (miRNA) expression in various cancers, there is limited information on the clinicopathologic significance of cancer-related miRNAs in esophageal squamous cell carcinoma (ESCC). Previously, it was reported that the expression of several miRNAs was dysregulated in ESCC. However, the target genes of these miRNAs have not been identified. Furthermore, additional miRNAs in humans have been discovered recently, indicating that revised miRNA and gene expression profiling for ESCC are necessary. Here, we provide datasets from microarray analyses to identify miRNA and mRNA expression comprehensively in Het-1A, a normal human esophageal squamous cell line, and three human ESCC cell lines.