Table of Contents
Diagnostic and Therapeutic Endoscopy
Volume 5, Issue 1, Pages 31-35

A 1000 cc Intragastric Balloon for Weight Reduction

1Gastroenterology Unit, Rambam Medical Center, Haifa, Israel
2Department of Laboratory Medicine, Rambam Medical Center, Haifa, Israel

Received 22 December 1997; Accepted 30 March 1998

Copyright © 1998 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective: To examine the efficiency of a 1000 cc intragastric balloon as an aid for weight reduction.

Subject: Thirty-three morbidly obese persons, after multiple attempts for weight loss.

Design: Intragastric 1000 cc balloons were endoscopically inserted into the stomachs of subjects. The balloons were left in place for six months. During that period the patients received dietary therapy. Hormone levels were measured prior to insertion and upon withdrawal of balloons.

Results: After a brief initial weight loss, most patients regained the weight initially lost. Mean weight loss after six months was only 8 kg (range 0–22 kg). We found that Bombesin levels, but not Gastrin levels, were significantly lower at the end of therapy than before insertion of the balloon.

Conclusion: We conclude that a large intragastric balloon for a prolonged time did not assist in weight loss. Our preliminary results show Bombesin levels change significantly, a finding which warrants further study.