Table of Contents
Diagnostic and Therapeutic Endoscopy
Volume 7, Issue 1, Pages 29-33

Percutaneous Dye Image Cardioscopy for Detection of Endocardial Lesions

1Cardiovascular Center, 564 Shioshizu, Sakura-shi, Chiba 285-0841, Japan
2Clinical Engineering Toho University Hospital at Sakura, 564 Shioshizu, Sakura-shi, Chiba 285-0841, Japan

Received 3 May 2000; Revised 15 June 2000; Accepted 15 June 2000

Copyright © 2000 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Endocardial lesions are caused not only by inflammatory processes but also by myocardial ischemia, resulting in endocardial thrombosis and cerebral embolism. We deviced a method for direct visualization of endocardial damages by a novel dye image cardioscopy with Evans blue and examined its feasibility in patients with heart disease. The dye was injected into the left ventricle before and after endomyocardial biopsy. Endocardial surface was stained in dark blue in 63% of patients with angina pectoris before biopsy. After biopsy, the biopsied portions were stained in blue in all. The results indicate that endocardium is damaged even in apparently intact LV in patients with ischemic heart disease and that endomyocardial biopsy causes severe endocardial damages.