Clinical Study

Duodenal Bulb Mucosa with Hypertrophic Gastric Oxyntic Heterotopia in Patients with Zollinger Ellison Syndrome

Figure 2

Microscopic images of endoscopic biopsy of the duodenum in patients with and without hypertrophic GOH. The relatively normal mucosa in patients and areas not affected by hypertrophic GOH (a) demonstrates some villous architecture alterations and gastric foveolar metaplasia, consistent with peptic type injury. The uninvolved duodenal sections had relatively tall villi, short crypts, and many mucinous glands both above and beneath the muscularis mucosa. The areas involved with hypertrophic GOH (b) demonstrated hypertrophic oxyntic gastric mucosa with mature parietal cells.
298381.fig.002a
(a)
298381.fig.002b
(b)