Table of Contents
Diagnostic and Therapeutic Endoscopy
Volume 2010, Article ID 278012, 3 pages
Clinical Study

Endoscopic Treatment of Vesicoureteral Reflux in Children with Dextranomer/Hyaluronic Acid—A Single Surgeon's 6-Year Experience

1Division of Pediatric Surgery, Department of Surgery, Taichung Veterans General Hospital, 160, Sec 3, Chung-Kang Road, Taichung 40705, Taiwan
2Department of Health, Taichung Hospital, Executive Yuan, 199, Sec 1, San Min Road, Taichung 40343, Taiwan

Received 13 March 2010; Revised 1 July 2010; Accepted 1 July 2010

Academic Editor: Manoj Monga

Copyright © 2010 Hou-Chuan Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Endoscopic treatment for vesicoureteral reflux (VUR) has become an established alternative to long-term antibiotic prophylaxis and ureteral reimplantation. We present the outcome of endoscopic treatment with dextranomer/hyaluronic acid copolymer (Deflux) for VUR in children by a single surgeon at our institute from October 2003 to October 2009. We reviewed the cases of 150 patients (total 239 ureters), 56 girls (37%) and 94 boys (63%), with a mean age of 2.2 years and a median followup of 2.5 years (range 3–68 months). Among the 239 ureters treated, 67.4% (161/239) were cured with a single injection, and a second and third injection raised the cure rate to 86.6% (207/239) and 88.3% (211/239), respectively. None had postoperative ureteral obstruction.