Table of Contents
Diagnostic and Therapeutic Endoscopy
Volume 2011, Article ID 507157, 6 pages
Clinical Study

Long-Term Results of Radiofrequency Energy Delivery for the Treatment of GERD: Results of a Prospective 48-Month Study

1Digestive Motility and Endoscopy Unit, Department of Medicine, ASO San Giovanni Battista Hospital, Via Genova 3, 10121 Turin, Italy
2Emergency Surgery Unit, Department of Emergency, ASO San Giovanni Battista Hospital, 10121 Turin, Italy
3Anesthesiology Unit, Department of Surgery, ASO San Giovanni Battista Hospital, 10121 Turin, Italy

Received 17 January 2011; Revised 18 June 2011; Accepted 17 August 2011

Academic Editor: Benjamin Kuttikatt Poulose

Copyright © 2011 Luca Dughera et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Since 2000, radiofrequency (RF) energy treatment has been increasingly offered as an alternative option to invasive surgical procedures for selected patients with gastroesophageal reflux disease (GERD). Out of 69 patients treated since June 2002 to December 2007 with the Stretta procedure, 56 of them reached by the end of 2010 a 48-month followup. RF treatment significantly improved heartburn scores, GERD-specific quality of life scores, and general quality of life scores at 24 and 48 months in 52 out of 56 patients (92,8%). At each control time both mean heartburn and GERD HRQL scores decreased ( 𝑃 = 0.001 and 𝑃 = 0.003, resp.) and both mental SF-36 and physical SF-36 ameliorated ( 𝑃 = 0.001 and 0.05, resp.). At 48 months, 41 out of 56 patients (72,3%) were completely off PPIs. Morbidity was minimal, with only one relevant but transient complication. According to other literature data, this study shows that RF delivery to LES is safe and durably improves symptoms and quality of life in well-selected GERD patients.