Table 3: Comparing the learning curve of different studies of CLE in the GI tract.

Present study Kuiper et al.
Gastrointest Endosc 2012 [5]
Buchner et al.
Gastrointest Endosc 2011 [6]
Neumann et al. Histol Histopathol 2011 [7]Gaddam et al. Am J Gastroenterol 2011 [8]

Type of confocal laserpCLEiCLEpCLEpCLEpCLE
TissueStomach (GIM)Colonic polypColonic polypColon (IBD)Esophagus (Barrett)
Number of reader531123
Number of center11311
Type of studyOffline studyOffline studyOffline studyOffline studyOffline study
Training duration1 hrN/A2 hrN/A1 hr
Intraobserver agreement (κ)N/AYes (0.68–0.84)N/AN/AN/A
Interobserver agreement (κ)Yes (0.52–0.86)Yes (0.67–0.73)N/AN/AYes (0.48–0.68)
ConclusionEasy to learnEasy to learnEasy to learnEasy to learnShort learning curve

pCLE: probe-based confocal laser endomicroscope, iCLE: integrated confocal laser endomicroscope, GIM: gastric intestinal metaplasia, IBD: inflammatory bowel disease, and N/A: no data.