Figure 3: SCC in middle esophagus (mucosal invasion: carcinoma in situ; depressed type; 11 mm). (a) NBI endoscopy revealed demarcated area brownish in color with NBI image visualization quality rated as fair for delineating approximately one-half of lesion margin circumference as remaining portion of lesion margin appeared dim (white arrows). (b) AFI endoscopy clearly revealed demarcated area magenta in color with AFI image visualization quality rated as excellent for delineating entire lesion margin circumference.