Figure 5: SCC in middle esophagus (mucosal invasion: carcinoma in situ; depressed type; 5 mm). (a) NBI endoscopy clearly revealed demarcated area brownish in color with NBI image visualization quality rated as excellent for delineating entire lesion margin circumference. (b) AFI endoscopy revealed demarcated area magenta in color with AFI image visualization quality rated as poor for delineating less than one-third of lesion margin circumference as most of lesion margin appeared dim (white arrows).