Figure 3: Seventy-two lesions biopsied from the Lugol-positive lesions were analyzed. The lesion observed as a well-demarcated brownish area with abnormal changes of intraepithelial papillary capillary loop (IPCL) pattern by NBI with magnification was defined as NBI positive. SCC squamous cell carcinoma; HGIN high-grade intraepithelial neoplasia; LGIN low-grade intraepithelial neoplasia; = number of lesions.