Research Article

Endoscopic Submucosal Dissection Outcomes for Gastroesophageal Tumors in Low Volume Units: A Multicenter Survey

Table 4

Summary of ESD in upper GI tract outcomes from low-volume centres in the world.

Taiwan [8]Italy [23]Portugal [27]France [19]South East Asia (this study)

Year2004–20072005–20112005–20082010–20132009–2015
Centers821145
Study methodRetrospectiveRetrospectiveRetrospectiveProspectiveRetrospective
Number of ESD cases702019177 (upper GI only)35
Size (mm)Mean Median 29 (15–60)Median 25 (15–30)Mean Median 20 (5–60)
Procedure time (minutes)Median 92.4 (25–210)Medial 119.1 (40–240)Median 90 (40–300)Mean Median 105 (15–480)
Knife usedIT knife
Needle knife
IT knife
Hook knife
IT knife
Hook knife
Dual knife
Flush knife
IT knife
Hybrid knife
Outcomes
 En bloc resection, (%)64/70 (91.4%)15/19 (79%)292/319 (91.5%)32/35 (91.4%)
 R0 en bloc resection, (%)NA18/20 (90%)13/19 (68%)277/319 (71.2%)27/32 (77.1%)
Complications
 Bleeding, (%)4/70 (5.7%)01/19 (5.3%)15 (4.7%)1 (2.9%)
 Perforation, (%)3/70 (4.3%)3/20 (15%)026 (8.1%)0
Recurrence
 Esophagus, (%)NA4/60 (6.7%)0
 Stomach, (%)2/70 2.8%NA05/63 (6.1%)2/35 (9.8%)

ESD: Endoscopic submucosal dissection; R0: complete resection with no margin involvement; NA: not available; and IT: insulated tip.