Review Article

Transitioning to Pegylated Interferon for the Treatment of Cutaneous T-Cell Lymphoma: Meeting the Challenge of Therapy Discontinuation and a Proposed Algorithm

Table 3

Prior therapies to interferon that were trialed in the presented cohort of patients.

PatientNumber of lines of treatment prior to IFNPreviously trialed therapies

11TCS, ECP
21TCS, ECP
4TCS, phototherapy (broad band), retinoids, radiation, methotrexate
43TCS, phototherapy, retinoids, radiation
9TCS, PUVA, TSEB, methotrexate, nitrogen mustard, interferon (2014–2016), chemotherapy, bortezomib, isotretinoin
7TCS, phototherapy, chemotherapy, retinoids, brentuximab vedotin
75TCS, PUVA, radiation, retinoids, imiquimod
4TCS, ECP, interferon (2016), retinoids (alitretinoin, isotretinoin)

Patients who received interferon before the course in which they were switched to pegylated interferon. TCS, topical corticosteroids; ECP, extracorporeal photopheresis; PUVA, psoralen + UVA; TSEB, total skin electron beam therapy; IFN, interferon.