Research Article
Clinical Characteristics, Treatment, and Prognosis of Amoxicillin-Induced AGEP/ALEP
Table 3
Laboratory and histological examination of 46 patients included.
| Parameter | Result |
| Laboratory test | White blood cell (31)a | | Leukocytosis | 31 (67.4%) | mm3 | 15495 (10800, 48700)b | Neutrophil (22)a | | Neutrophilia | 22 (47.8%) | mm3 | 12850 (7880, 29140)b | C-reactive protein (16)a | | Normal | 1 (2.2%) | Elevated | 15 (32.6%) | mg/L | 138 (7.2, 323.4)b | Erythrocyte sedimentation rate (6)a | | Normal | 2 (4.3%) | Elevated | 4 (8.7%) | Cultures (20)a | | Negative | 19 (41.3%) | Positive | 1 (2.2%) | Skin biopsy (31)a | | Epidermis | | Subcorneal pustule | 22 (47.8%) | Spongy pustules | 14 (30.4%) | Acanthosis | 4 (8.7%) | Necrotic keratinocytes | 4 (8.7%) | Derma | | Papillary edema | 7 (15.2%) | Capillary thrombosis | 1 (2.2%) | Inflammatory cell infiltrate | 26 (56.5%) | Neutrophilic infiltrate | 4 (8.7%) | Lymphohistiocytic infiltrate | 2 (4.3%) | Eosinophils infiltrate | 1 (2.2%) | Mixed inflammatory infiltrate | 18 (39.1%) | Lymphocyte transformation tests (2)a | | Positive | 2 (4.3%) | Patch tests (19)a | | Negative | 1 (2.2%) | Positive | 18 (39.1%) | Skin prick tests (3)a | | Positive | 3 (6.5%) | IL-36RN gene (4)a | | p.Leu27Pro | 1 (2.2%) | p.Ser113Leu | 1 (2.2%) | c.C338T:p.S113L | 1 (2.2%) | p.Arg10X and p.Arg10ArgfsX1 | 1 (2.2%) |
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aThe number of patients out of 46 about whom information regarding this particular parameter was provided. bMedian (minimum-maximum).
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