Review Article
MicroRNAs as Potential Biomarkers for the Diagnosis, Treatment, and Prognosis of Sexually Transmitted Diseases: Recent Advances and Future Directions
Table 2
MiRNAs modulate syphilis infection by regulating host proteins.
| miRNA | Target(s) | Action | Experimental strategy | References |
| miR-195-5p/miR223-3p/miR-589-3p | Several genes | Diagnostic tool and predictor of serological response | In vitro | [27] | miR-101-3p | TLR2 3, UTR | Macrophage cytokine decreased | In vitro | [29] | miR-338-5p | RANBP 17, XPO 1 and XPO 6 | Identification of patients with serological fixation and diagnosis of latent syphilis | In vitro | [26] | miR-142-3p | DC | Promoting the progression of syphilis infection | In vitro | [30] |
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