Identification of a Functional Type IA Topoisomerase, LdTopIIIβ, from Kinetoplastid Parasite Leishmania donovani

Figure 1

Amino acid sequence alignment. Sequence of LdTopIIIβ (Ld) was aligned with the amino acid sequences of H. sapiens topoisomerase IIIβ (Hs), topoisomerase III from S. cerevisiae (Sc) and S. pombe (Sp) using CLUSTAL W. The amino acids are numbered on the top of the sequences. Active site motifs and other important conserved and identical residues are depicted in red. Green and blue indicate strongly similar and weakly similar amino acids, respectively.