Research Article

Identification of a Functional Type IA Topoisomerase, LdTopIIIβ, from Kinetoplastid Parasite Leishmania donovani

Table 1

Amino acids homology comparisons between Leishmania donovani topoisomerase III (866 amino acids) and other members of typeIA topoisomerases.

Type IA topoisomerasesIdentity (%)Similarity (%)Size (amino acids)

LdTopIIIα28.5459.66947
LdTopIA13.2248.56812
Human TopIIIα27.1455.471001
Human TopIIIβ46.2276.09862
S. cerevisiae TopIII22.9647.33656
S. pombe TopIII22.5649.32622