Research Article

Towards Al3+-Induced Manganese-Containing Superoxide Dismutase Inactivation and Conformational Changes: An Integrating Study with Docking Simulations

Figure 6

The kinetics of Al3+-induced fluorescence spectra changes. (a) Plot of maximum intensity versus time (min). Intrinsic fluorescence spectra changes were measured in response to 0.2 mM Al3+ for various time intervals. The final Mn-SOD concentration was 1.6 μM. (b) A semilogarithmic plot. (●) Experimental points. (+) Points obtained by subtracting the contribution of the slow phase from the data in the curve (- - -). : maximum intensity at various time interval; : maximum intensity at equilibrated state; : maximum intensity at initial state.
307464.fig.006a
(a)
307464.fig.006b
(b)