Enzyme Research

Enzyme Research / 2011 / Article / Fig 5

Review Article

Therapeutic Implications of Targeting AKT Signaling in Melanoma

Figure 5

Akt is the key regulator of cell survival and proliferation. Growth factors and hormones trigger the Akt pathway by a series of phosphorylation and dephosphorylation events. Shown are some of the substrates of Akt implicated in cell survival, proliferation, and migration.

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