The Roles of ADAMs Family Proteinases in Skin Diseases

Figure 1

Schematic of domain structure of ADAM proteinases. P: propeptide domain, M: metalloproteinase domain, D: disintegrin domain, CR: cysteine-rich domain, EGF: EGF-like domain, T: transmembrane domain, C: cytoplasmic domain, SP: spacer domain, TS: thrombospondin type I motif.