Interaction between Calcineurin and Ca2+/Calmodulin Kinase-II in Modulating Cellular Functions
Figure 1
A schematic representation of the model for the regulation of the inwardly rectifying K+ channels in renal tubule cells by phosphorylation and dephosphorylation processes. CaN is often called protein phosphatase-2B (PP-2B). The circled “P” indicates phosphate. Circled “+” and “−” indicate stimulation and inhibition, respectively. Small squares attached to the lower part of the channel are putative phosphorylation sites. See text for details.
