A Fractional Factorial Design to Study the Effect of Process Variables on the Preparation of Hyaluronidase Loaded PLGA Nanoparticles

<div>Contour plot showing the effect of independent variables on percentage drug encapsulation. (a) Effect of various levels of internal-external phase volume ratio and PVA concentration on percentage drug encapsulation when the levels of other variables are maintained at low levels. (b) Effect of various levels of internal-external phase volume ratio and PVA concentration on percentage drug encapsulation when the levels of other variables are maintained at high levels.</div>

Enzyme Research

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Figure 5

Figure 5: A Fractional Factorial Design to Study the Effect of Process Variables on the Preparation of Hyaluronidase Loaded PLGA Nanoparticles 