Mode of Action of Lactoperoxidase as Related to Its Antimicrobial Activity: A Review
Figure 5
Target group of hypothiocyanite, hypoiodite, and iodine. Due to its low oxidation power, hypothiocyanite is relatively specific and is not reactive against all thiols. In vivo, hypoiodite seems to be selectively directed against reduced pyridine nucleotide because even the presence of excess glutathione and methionine does not thoroughly inhibit their oxidation. HOSCN/OSCNā: acidic or basic form of hypothiocyanite; HOI/OIā: acidic or basic form of hypoiodite; and I2: iodine.
