Research Article

Salivary Myeloperoxidase, Assessed by 3,3′-Diaminobenzidine Colorimetry, Can Differentiate Periodontal Patients from Nonperiodontal Subjects

Table 2

Diagnostic efficacy of MPO assay in differentiation between healthy subjects and periodontal disease patients.

Comparative groupsROC curve parameters Sensitivity (%) (95% CI) Specificity (%) (95% CI) Predictive value (%) (95% CI)
Cut-off valueAUC
(95% CI)
PositiveNegative

Healthy versus gingivitis and periodontitis0.1060.743 (0.586–0.901)94.12 (83.76–98.77)54.55 (23.38–83.25)90.57 (79.34–96.87)66.67 (29.93–92.51)

Healthy and gingivitis versus periodontitis0.3650.749 (0.627–0.872)68.42 (43.45–87.42)81.40 (66.60–91.61)61.90 (38.44–81.89)85.37 (70.83–94.43)

CI: confidence interval.
The cut-off value was calculated using the receiver operating characteristic curve (ROC) method.
Sensitivity, specificity, and positive and negative predictive values were analyzed by using area under ROC (AUC).
ROC plot displayed true positive sensitivity and false positive.