Research Article

Authentication of Algorithm to Detect Metastases in Men with Prostate Cancer Using ICD-9 Codes

Table 1

Validity of diagnoses codes of metastases to prostate cancer.

Medical chart review
 ClaimsYesNo

Algorithm A  Yes580
(ICD 198.5 or 198.3 or 197.0 or 197.7) No3231
 Total61231
 Sensitivity58/61 = 0.95 (0.86, 0.99)
 Specificity231/231 = 1 (0.98, 1.00)
 PPV58/58 = 1 (0.94, 1.00)
 NPV231/234 = 0.99 (0.96, 0.99)

Algorithm B  Yes550
(ICD 198.5) No6231
 Total61231
 Sensitivity55/61 = 0.90 (0.80, 0.96)
 Specificity231/231 = 1 (0.98, 1.00)
 PPV55/55 = 1 (0.94, 1.00)
 NPV231/237 = 0.97 (0.95, 0.99)