Factors Associated with a Poor Treatment Outcome among Children Treated for Malaria in Ibadan, Southwest Nigeria

Table 3

Illness history associated with outcome.

	Full recovery	Recovery + NC or death	Chi-square	𝑃 value
Any home treatment
Yes	1683 (89.9)	189 (10.1)
No	524 (90.5)	55 (9.5)	0.936	0.776
Any drug used prior to presentation (𝑁=2240)
Yes	1553 (98.9)	17 (1.1)
No	649 (96.9)	21 (3.1)	11.852	0.001
Drug used prior to presentation
PCM
Yes	1442 (99.0)	15 (1.0)
No	757 (97.1)	23 (2.9)	11.206	0.001
CQ
Yes	346 (98.3)	6 (1.7)
No	1853 (98.3)	32 (1.7)	0.000	1.000
AQ (2237)
Yes	93 (97.9)	2 (2.1)
No	2106 (98.3)	36 (1.7)	0.098	1.000
SP
Yes	21 (95.5)	1 (4.5)
No	2178 (98.3)	37 (1.7)	1.078	0.315
Symptoms prior to presentation
Fever; (𝑛=2468)
Yes	2165 (89.6)	250 (10.4)	2.426	0.116
No	44 (83.0)	9 (17.0)
Rigors; (𝑛=2468)
Yes	407 (92.9)	31 (7.1)	6.618	0.010*
No	1802	228 (11.2)
Loss of appetite (𝑛=2468)
Yes	912 (94.4)	54 (5.6)	40.644	<0.0001*
No	1297 (86.4)	205 (13.6)
Vomiting (𝑛=2468)
Yes	812 (91.2)	78 (8.8)	4.437	0.040*
No	1397 (88.5)	181 (11.5)
Diarrhoea (𝑛=2468)
Yes	142 (90.4)	15 (9.6)	0.158	0.788
No	2067 (89.4)	244 (10.6)
Jaundice (𝑛=2468)
Yes	56 (73.7)	20 (26.3)
No	2153 (90.0)	239 (10.0)	20.897	0.0001*
Pallor (𝑛=2467)
Yes	379 (92.7)	30 (7.3)	5.222	0.022*
No	1829 (88.9)	229 (11.1)
Fast breathing (𝑁=2468)
Yes	140 (87.0)	21 (13.0)	1.192	0.286
No	2069 (89.7)	238 (10.3)
Lethargy (𝑛=2468)
Yes	298 (87.9)	41 (12.1)	1.071	0.295
No	1911 (89.8)	218 (10.2)
Loss of consciousness (𝑛=2240)
Yes	197 (93.4)	14 (6.6)	34.069	<0.0001*
No	2005 (98.8)	24 (1.2)
Convulsion (𝑛=2466)
Yes	449 (83.9)	86 (16.1)	22.566	<0.0001*
No	1758 (91.0)	173 (9.0)

∗Statistically significant.