Evolution and Prospects for Intracranial Pharmacotherapy for Refractory Epilepsies: The Subdural Hybrid Neuroprosthesis
Figure 1
An example of severe focal neocortical epilepsy not amenable to complete tissue resection. (a) Schematic representation of the intracranial electrode array implanted for localization of the ictal onset zone. The ictal onset is shown by magenta-colored electrode circles. Eloquent and motor/sensory cortices, determined by functional mapping, are shown with colored bars between electrode pairs; red: language area, cyan: motor area; blue: sensory area. The overlap of the ictal onset zone with language areas excludes the option of full resection of the epileptogenic tissue. (b) Focal ictal discharge in the left posterior temporal region highlighted by magenta arrows: note overlap with language areas.
