Blood-Brain Barrier Dysfunction in Epileptogenesis of the Temporal Lobe
Figure 3
Spontaneous seizures induced by albumin. (a) An X-ray photograph of mouse implanted with FITC-BSA infusion pump and telemetric electrographic recording transmitter. (b) FITC conjugated BSA preferentially accumulates in the hippocampus after intraventricular infusion. (c) Electrographic recording (upper panel) of a spontaneous seizure 4 days after pump implant, and the corresponding spectrogram (lower panel). (d) Ictal activity (slower time scale).