Characterization of the Gene Expression Profile of Human Hippocampus in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis
Figure 1
Cluster analysis of the gene expression patterns of isolated MVECs () and AHEs () from patients with MTLE after selective amygdalohippocampectomy (sAHE) and control hippocampal tissue specimens (). The analysis was performed using GeneSpring software. The analysis included all differentially expressed genes expressed in oligonucleotide microarray analysis (Affymetrix, HG-U133Plus2.0). Each horizontal colour bar denotes the intensity of expression of a particular gene in a distinct sample relative to the mean expression value of all samples. Yellow denotes little or no change, red denotes increased expression, and blue denotes decreased expression. AHE: amygdalohippocampectomy, MVEC: microvascular endothelial cells, and C: control.
